The Causes of Dry Mouth

Sjögren’s Syndrome1

 

  • Up to
    3 Mil
    Americans are affected by this syndrome each year
     
  • More than
    90%
    Of Sjögren's sufferers are women, and about 50% also have rheumatoid arthritis
Dry mouth is commonly associated with a condition known as Sjögren’s syndrome, a chronic, autoimmune disease in which the body’s immune system attacks its own moisture-producing glands. Because of this, all patients with Sjögren’s experience dry mouth to some degree. During the course of the disease, immune cells attack and destroy gland tissue, reducing its ability to function and produce fluid. Sjögren’s disease may also cause dryness of other organs, such as the kidneys, gastrointestinal system, blood vessels, lung, liver, pancreas, and the central nervous system.

 


Medications

Overactive Bladder Medications

Medications used to treat urological conditions such as overactive bladder (OAB) can lead to dry mouth. These medications are associated with causing dry mouth because of the way they work. The simple explanation is that they “dry out” the system. This drying out affects the whole body and therefore reduces the secretion of saliva. Dry mouth is a common side effect of medications used to treat OAB.

Physicians treating overactive bladder may be able to anticipate their patients' dry mouth symptoms and prescribe an effective treatment such as Aquoral as part of therapy

Psychiatric Medications

Medications such as selective serotonin reuptake inhibitors (SSRIs) and others that are prescribed to treat a number of psychiatric conditions (including depression, anxiety, schizophrenia, bipolar disorder) are frequently associated with dry mouth. Speak to your doctor if you think you may be experiencing dry mouth as a side effect of medications you are taking.

Multiple Medications

Dry mouth may be the consequence of a number of diseases, including diabetes, HIV, hepatitis C, lupus, and depression.2

Aquoral four-pack product photo

Aquoral™ can provide relief from the symptoms of dry mouth caused by medications.

It relieves chronic and temporary symptoms of dry mouth such as difficulties in swallowing, speech, and changes in taste.

Allow at least 3 days of regular use for optimal results.3,4


Aging

Although reductions in saliva production occur as a natural part of aging, the most pervasive cause of dry mouth in older persons is the use of 1 or more xerogenic, or dry mouth-causing, medications.1

The risk of dry mouth increases as more medications are taken, a common situation among elderly patients.

Aquoral™ can provide relief from the symptoms of dry mouth associated with aging.

It relieves chronic and temporary symptoms of dry mouth such as difficulties in swallowing, speech, and changes in taste.

Allow at least 3 days of regular use for optimal results.3,4

Aquoral four-pack product photo

Lifestyle Activities

Certain activities can cause dry mouth or make existing dry mouth even worse. Such activities include smoking, drinking alcohol or caffeine, public speaking, anxiety, and stress. Dry mouth is one of many great reasons to quit smoking! Any type of tobacco, even smokeless tobacco, can aggravate dry mouth. Alcohol and caffeine are also well known to lead to loss of moisture. Dry mouth is frequently associated with other health issues, such as high blood pressure.


Cancer Therapy

A very common side effect of radio- and chemotherapy used to treat a variety of cancer types is dry mouth.5 Radiation therapy for head and neck cancer often damages the salivary glands, which are responsible for making and releasing saliva in your mouth. The goal of chemotherapy is to eradicate fast growing cancer cells, but it may also damage other fast growing cells in your body, including those that produce saliva.6 As a result, cancer therapy patients may experience severe dry mouth symptoms such as:

  • Dry or cracked lips
  • Mouth sores and infections
  • Periodontal disease and cavities
  • Difficulty with chewing, swallowing, and tasting food
  • Difficulty with speaking
  • A burning feeling
  • Thick or stringy saliva

Dry mouth can occur early in the course of treatment and continue even after treatment ends, with some people experiencing life-long symptoms. As a result, dry mouth is one of the most troubling side effects of treatment—and it can greatly impact quality of life. Fortunately, there is a novel prescription treatment that may provide relief from the symptoms of dry mouth: Aquoral.

Aquoral can provide relief from the symptoms of dry mouth caused by cancer therapy.7

It relieves chronic and temporary symptoms of dry mouth such as difficulties in swallowing, speech, and changes in taste.

Allow at least 3 days of regular use for optimal results.3,4


References:

  1. Wise, Christopher. Sjögren's Syndrome. Lake Boulevard: American College of Rheumatology, 2012.
  2. Data on file. OGT Spray: A Clinically Proven New Option for Treating Xerostomia. Laboratoires Carliène.
  3. Mouly SJ, Orler J-B, Tillet Y, et al. Efficacy of a new oral lubricant solution in the management of psychotropic drug-induced xerostomia: arandomized, controlled trial. J Clin Psychopharmacol. 2007;27(5):437-443.
  4. Mouly SJ, Salom M, Tillet Y, et al. Management of xerostomia in older patients: arandomised controlled trial evaluating the efficacy of a new oral lubricant solution. Drugs Aging. 2007;24(1):957-965.
  5. Wong HM. Oral complications and management strategies for patients undergoing cancer therapy. Scientific World J. 2014;
  6. US Dept Health and Human Services. Agency for Healthcare research and Quality. Understanding Radiotherapy for Head and Neck Cancer: A guide for Adults and their Caregivers. Accessed October 1, 2014.
  7. Data on file. Medical and technical dossier. OGT oral spray. May 2005. San Antonio: TX. Mission Pharmacal Company; 2014.
  8. Aquoral [package insert]. San Antonio: TX. Mission Pharmacal Company; 2014.